Streptococcus pneumoniae favors tolerance via metabolic adaptation over resistance to circumvent fluoroquinolones

ABSTRACT Streptococcus pneumoniae is a major human pathogen of global health concern and the rapid emergence of antibiotic resistance poses a serious public health problem worldwide.Fluoroquinolone resistance in S.pneumoniae is an intriguing case because the prevalence of fluoroquinolone resistance does not correlate with increasing usage and has r

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